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Activation of a heterodimeric receptor complex comprised of the IL-13 receptor α1 subunit (IL-13Rα1) and the IL-4 receptor α subunit (IL-4α) by IL-13 and IL-4.
Abbreviations: IL, interleukin; JAK, Janus kinase; STAT, signal transducer and activator of transcription; Tyk, tyrosine kinase.
