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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Cell Signal. 2017 May 8;36:154–162. doi: 10.1016/j.cellsig.2017.05.007

Figure 4. ER stress reduces pFAK through tyrosine phosphatases and calcium.

Figure 4

bEnd5 cells were treated with TG or TM for 48 or 72 h with or without the tyrosine phosphatase inhibitor bpV or calcium channel blocker APB.A) bpV prevented the loss of pFAK caused by ER stress, as shown in a Western blot. tFAK = total FAK, α-tubulin was used as a loading control. B) APB completely rescued pFAK against TG, but not against TM. This was accompanied by similar effects on pS727-STAT3. tSTAT3 = total STAT3. Blots in A and B are representative of n=3.