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. 2017 Sep 7;12(9):e0184258. doi: 10.1371/journal.pone.0184258

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© 2017 Takase et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (a) Protein (20 μg) from lysates of each animal in pre-stroke, 6, and 16 weeks after MCAO was analyzed. (b-d) Quantitative analysis of expression level in LOTUS, Nogo-A, and NgR1. Immunoblots were normalized with β-actin. (b) Increases in LOTUS expression in the non-ischemic side of both WT and LOTUS-Tg mice 6 weeks after MCAO were found. (c, d) No significant difference was seen in Nogo-A and NgR1 expression. (2-way ANOVA with Tukey post hoc analysis; **p < 0.01. Data are mean ± S.E.M. n = 3).