Fig 3. Reduction of tyrosine hydroxylase (TH)+ neurons after 6-hydroxydopamine (6-OHDA) administration.
(A) Representative images of dopaminergic neurons in the posterior tuberculum and noradrenergic neurons in the locus coeruleus. Right panel: magnified pictures of the red square regions are shown. (B) The numbers of dopaminergic neurons in the posterior tuberculum and noradrenergic neurons in the locus coeruleus are significantly decreased by 6-OHDA treatment in 12-month-old zebrafish; n = 5 fish per group. Bars represent the SEM. **, p < 0.01, ***, p < 0.001.