Table 2. Common DE genes regulated by the enrichment of STK4 in three subcellular locations (FDR ≤ 0.01).
Numbers are in log2 fold change. Minus signs indicate downregulation with respect to the vector control.
| Entrez ID | Gene Symbol | CL-STK4 | LR-STK4 | NL-STK4 | Entrez ID | Gene Symbol | CL-STK4 | LR-STK4 | NL-STK4 |
|---|---|---|---|---|---|---|---|---|---|
| 23316 | CUX2 | -1.61 | 2.64 | 2.8 | 3113 | HLA-DPA1 | 2.03 | 4.98 | 4.8 |
| 3087 | HHEX | -2.09 | 2.33 | 2.4 | 3239 | HOXD13 | 1.70 | 7.53 | 7.6 |
| 3400 | ID4 | -2.00 | 3.57 | 3.5 | 11255 | HRH3 | -1.53 | -3.61 | -3.8 |
| 5064 | PALM | -2.19 | 2.76 | 2.8 | 9951 | HS3ST4 | -3.12 | -4.71 | -5.3 |
| 6091 | ROBO1 | -1.63 | 2.79 | 2.8 | 3434 | IFIT1 | 1.86 | 2.86 | 2.7 |
| 80031 | SEMA6D | -4.13 | 4.25 | 4.3 | 3479 | IGF1 | -3.24 | -6.94 | -8.7 |
| 57713 | SFMBT2 | -1.60 | 4.41 | 4.4 | 3751 | KCND2 | -1.58 | -3.06 | -3.7 |
| 57007 | ACKR3 | 2.87 | -2.45 | -5.7 | 57562 | KIAA1377 | 2.32 | 3.17 | 2.9 |
| 6364 | CCL20 | 1.74 | -3.12 | -4.5 | 3798 | KIF5A | 2.68 | 6.71 | 6.6 |
| 51816 | CECR1 | 2.08 | -2.60 | -2.6 | 55243 | KIRREL | 3.62 | 6.78 | 6.8 |
| 170712 | COX7B2 | 2.12 | -2.71 | -3.9 | 84894 | LINGO1 | 1.84 | 3.70 | 3.9 |
| 1644 | DDC | 2.84 | -3.41 | -7.1 | 54947 | LPCAT2 | 1.92 | 4.68 | 5.0 |
| 8653 | DDX3Y | 2.06 | -4.39 | -7.1 | 84230 | LRRC8C | 1.99 | 5.70 | 5.6 |
| 9086 | EIF1AY | 1.85 | -3.23 | -5.2 | 130576 | LYPD6B | 2.36 | 2.40 | 3.1 |
| 9518 | GDF15 | 2.03 | -6.69 | -7.5 | 4117 | MAK | -1.67 | -2.40 | -2.3 |
| 219970 | GLYATL2 | 1.55 | -3.86 | -6.0 | 22983 | MAST1 | 1.50 | 2.29 | 2.3 |
| 3158 | HMGCS2 | 2.49 | -3.53 | -7.1 | 154141 | MBOAT1 | 1.71 | 4.01 | 4.1 |
| 153572 | IRX2 | 1.76 | -3.08 | -3.6 | 2122 | MECOM | 2.76 | 5.13 | 5.0 |
| 8284 | KDM5D | 1.64 | -3.18 | -5.7 | 4233 | MET | 3.42 | 6.10 | 6.2 |
| 3934 | LCN2 | 2.35 | -3.90 | -4.9 | 11320 | MGAT4A | 2.14 | 3.91 | 3.9 |
| 57633 | LRRN1 | 1.73 | -4.01 | -6.5 | 4281 | MID1 | 2.09 | 7.94 | 7.8 |
| 4100 | MAGEA1 | 1.84 | -3.60 | -7.4 | 4285 | MIPEP | -1.52 | -2.76 | -2.4 |
| 4316 | MMP7 | 5.48 | -3.03 | -3.6 | 26002 | MOXD1 | 2.85 | 7.08 | 7.6 |
| 22829 | NLGN4Y | 1.53 | -3.68 | -4.3 | 4664 | NAB1 | 2.07 | 3.12 | 3.3 |
| 10158 | PDZK1IP1 | 1.51 | -4.07 | -6.6 | 57701 | NCKAP5L | 1.62 | 2.41 | 2.6 |
| 5284 | PIGR | 1.82 | -2.72 | -2.8 | 23114 | NFASC | 1.57 | 2.58 | 2.3 |
| 8612 | PPAP2C | 1.89 | -3.94 | -5.9 | 7025 | NR2F1 | 1.61 | 3.62 | 3.3 |
| 64063 | PRSS22 | 1.73 | -3.55 | -4.1 | 2908 | NR3C1 | 2.58 | 8.50 | 8.3 |
| 5696 | PSMB8 | 2.53 | -2.10 | -2.6 | 4922 | NTS | 2.08 | 4.71 | 4.7 |
| 6192 | RPS4Y1 | 2.20 | -3.63 | -7.8 | 93145 | OLFM2 | 2.42 | 2.62 | 2.5 |
| 5268 | SERPINB5 | 1.65 | -4.31 | -5.5 | 10133 | OPTN | 2.20 | 2.02 | 2.1 |
| 8764 | TNFRSF14 | 1.62 | -3.95 | -4.2 | 390190 | OR5B2 | -2.17 | -3.93 | -4.5 |
| 7367 | UGT2B17 | 1.63 | -2.16 | -4.7 | 5066 | PAM | 1.87 | 3.88 | 4.0 |
| 8287 | USP9Y | 3.16 | -2.47 | -6.6 | 64881 | PCDH20 | 2.63 | 2.51 | 2.9 |
| 7404 | UTY | 2.08 | -2.79 | -4.9 | 56034 | PDGFC | 2.02 | 6.40 | 6.4 |
| 728763 | AC104809.3 | -1.89 | -4.27 | -4.9 | 114770 | PGLYRP2 | -2.23 | -5.75 | -6.8 |
| 2181 | ACSL3 | -2.39 | -3.23 | -3.1 | 5241 | PGR | 2.90 | 6.04 | 6.1 |
| 23305 | ACSL6 | 1.75 | 3.86 | 3.6 | 5569 | PKIA | 2.53 | 5.84 | 5.9 |
| 10863 | ADAM28 | -2.48 | -4.17 | -3.6 | 51365 | PLA1A | -2.18 | -5.94 | -6.6 |
| 8756 | ADAM7 | -4.84 | -7.51 | -8.2 | 440107 | PLEKHG7 | -1.51 | -3.55 | -4.1 |
| 150 | ADRA2A | -1.72 | -4.08 | -5.9 | 5352 | PLOD2 | 1.57 | 3.94 | 4.3 |
| 100130776 | AGAP2-AS1 | 1.58 | 3.05 | 3.4 | 84898 | PLXDC2 | 3.94 | 3.66 | 3.4 |
| 10551 | AGR2 | -3.40 | -7.05 | -7.1 | 56937 | PMEPA1 | -1.60 | -5.13 | -5.6 |
| 183 | AGT | -1.96 | -4.95 | -5.1 | 57718 | PPP4R4 | 1.93 | 2.56 | 2.8 |
| 57491 | AHRR | 1.52 | 5.95 | 6.2 | 5743 | PTGS2 | 1.53 | 2.96 | 3.8 |
| 115701 | ALPK2 | -2.23 | -3.52 | -3.7 | 5796 | PTPRK | 1.97 | 3.36 | 3.3 |
| 347902 | AMIGO2 | 1.83 | 3.16 | 3.3 | 284119 | PTRF | 2.13 | 2.65 | 2.9 |
| 319 | APOF | -1.82 | -4.53 | -4.7 | 138046 | RALYL | -2.96 | -6.93 | -7.6 |
| 79822 | ARHGAP28 | -1.51 | -2.60 | -2.6 | 11069 | RAPGEF4 | 1.51 | 4.05 | 4.2 |
| 115557 | ARHGEF25 | 1.81 | 2.30 | 2.4 | 85004 | RERG | 2.02 | 3.99 | 4.3 |
| 26053 | AUTS2 | 1.78 | 3.23 | 3.1 | 10287 | RGS19 | 1.70 | 3.28 | 3.3 |
| 563 | AZGP1 | -1.83 | -7.37 | -10.2 | 58480 | RHOU | -2.10 | -2.27 | -2.4 |
| 25825 | BACE2 | 1.98 | 3.56 | 3.5 | 9783 | RIMS3 | 2.37 | 2.45 | 2.4 |
| 54796 | BNC2 | 2.07 | 4.92 | 4.9 | 140730 | RIMS4 | 1.51 | 6.12 | 6.2 |
| 89927 | C16orf45 | 1.92 | 2.32 | 2.2 | 57484 | RNF150 | 1.54 | 4.52 | 4.6 |
| 767 | CA8 | 3.00 | 6.92 | 7.3 | 221687 | RNF182 | 2.10 | 3.82 | 3.8 |
| 57118 | CAMK1D | 1.91 | 3.68 | 3.9 | 6286 | S100P | -2.03 | -6.00 | -5.5 |
| 858 | CAV2 | 3.15 | 6.26 | 6.5 | 55511 | SAGE1 | -2.23 | -4.94 | -5.6 |
| 285025 | CCDC141 | -2.76 | -4.30 | -4.8 | 389432 | SAMD5 | 2.55 | 3.04 | 3.0 |
| 159989 | CCDC67 | -2.41 | -4.89 | -5.5 | 54809 | SAMD9 | 2.68 | 3.25 | 3.8 |
| 151887 | CCDC80 | 2.66 | 5.68 | 5.3 | 6326 | SCN2A | 2.46 | 4.71 | 4.6 |
| 9308 | CD83 | 1.68 | 2.84 | 2.7 | 56256 | SERTAD4 | 2.46 | 6.28 | 6.1 |
| 64781 | CERK | 2.54 | 5.64 | 5.7 | 9644 | SH3PXD2A | 1.59 | 3.65 | 3.8 |
| 1135 | CHRNA2 | -2.40 | -7.59 | -8.3 | 6565 | SLC15A2 | -1.65 | -2.46 | -2.1 |
| 9435 | CHST2 | 2.14 | 4.65 | 4.9 | 7781 | SLC30A3 | 2.20 | 5.05 | 5.0 |
| 7123 | CLEC3B | -1.51 | -3.95 | -4.1 | 55089 | SLC38A4 | -3.73 | -2.73 | -2.1 |
| 80034 | CSRNP3 | 2.12 | 3.16 | 3.2 | 85414 | SLC45A3 | -1.65 | -6.16 | -6.0 |
| 1519 | CTSO | -1.57 | -2.58 | -2.2 | 146857 | SLFN13 | 2.50 | 3.17 | 3.0 |
| 10563 | CXCL13 | -2.96 | -4.32 | -4.4 | 84189 | SLITRK6 | -1.68 | -3.89 | -3.5 |
| 80319 | CXXC4 | 2.35 | 5.90 | 5.8 | 8406 | SRPX | 2.25 | 2.73 | 2.8 |
| 260293 | CYP4X1 | 2.04 | 2.66 | 3.1 | 7903 | ST8SIA4 | 2.61 | 2.73 | 3.4 |
| 1740 | DLG2 | -2.69 | -3.44 | -3.8 | 6769 | STAC | 2.32 | 4.58 | 4.6 |
| 93099 | DMKN | 1.60 | 5.54 | 5.8 | 112755 | STX1B | 1.83 | 4.45 | 4.9 |
| 10655 | DMRT2 | -1.69 | -3.91 | -4.0 | 55061 | SUSD4 | 1.54 | 2.47 | 3.0 |
| 1846 | DUSP4 | -2.64 | -3.71 | -3.5 | 221711 | SYCP2L | 1.75 | 4.82 | 4.8 |
| 80303 | EFHD1 | 1.50 | 4.55 | 4.8 | 23345 | SYNE1 | 1.90 | 4.46 | 4.4 |
| 22936 | ELL2 | -1.84 | -3.10 | -2.8 | 11346 | SYNPO | 1.52 | 2.86 | 2.7 |
| 54898 | ELOVL2 | -3.41 | -2.33 | -2.1 | 6857 | SYT1 | 1.72 | 4.63 | 5.0 |
| 60481 | ELOVL5 | -1.64 | -3.23 | -3.1 | 6860 | SYT4 | -2.92 | -6.38 | -8.5 |
| 79993 | ELOVL7 | -1.58 | -4.17 | -4.3 | 80731 | THSD7B | -1.91 | -3.73 | -4.0 |
| 2026 | ENO2 | 1.95 | 3.18 | 3.4 | 23671 | TMEFF2 | -4.99 | -6.34 | -6.3 |
| 2042 | EPHA3 | -4.00 | -5.75 | -5.9 | 55321 | TMEM74B | 2.55 | 3.90 | 3.7 |
| 2119 | ETV5 | 1.88 | 3.40 | 4.3 | 3371 | TNC | 1.71 | 4.63 | 3.9 |
| 90362 | FAM110B | -1.55 | -2.47 | -2.4 | 55504 | TNFRSF19 | -2.70 | -4.63 | -4.6 |
| 9715 | FAM131B | 1.85 | 3.45 | 4.1 | 23043 | TNIK | 1.64 | 3.97 | 3.8 |
| 23359 | FAM189A1 | 2.02 | 2.02 | 2.0 | 84951 | TNS4 | -1.94 | -5.00 | -5.3 |
| 2217 | FCGRT | 2.29 | 4.06 | 4.2 | 10345 | TRDN | -1.76 | -5.87 | -6.3 |
| 9638 | FEZ1 | 1.90 | 2.14 | 2.8 | 117854 | TRIM6 | 1.74 | 4.92 | 5.0 |
| 2289 | FKBP5 | -2.12 | -2.50 | -2.3 | 7220 | TRPC1 | 1.89 | 6.36 | 6.6 |
| 121643 | FOXN4 | 2.14 | 2.19 | 2.2 | 162514 | TRPV3 | -2.41 | -3.49 | -3.7 |
| 53827 | FXYD5 | 2.27 | 6.68 | 7.0 | 10100 | TSPAN2 | 1.78 | 5.64 | 6.1 |
| 2550 | GABBR1 | 2.15 | 2.39 | 2.2 | 7102 | TSPAN7 | 4.40 | 5.84 | 5.8 |
| 2706 | GJB2 | 1.72 | 2.16 | 3.1 | 23508 | TTC9 | 1.55 | 2.72 | 2.7 |
| 647309 | GMNC | -1.95 | -3.46 | -5.3 | 10382 | TUBB4A | 1.52 | 2.80 | 2.8 |
| 387509 | GPR153 | 1.50 | 3.25 | 3.1 | 54490 | UGT2B28 | -2.08 | -4.54 | -5.2 |
| 2982 | GUCY1A3 | -1.75 | -3.47 | -3.3 | 79674 | VEPH1 | -2.65 | -5.42 | -6.2 |