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. 2017 Sep-Oct;5(5):1169–1178. doi: 10.1016/j.jaip.2017.06.031

Table III.

Population-based data for rate of fatal anaphylaxis triggered by insect venom

Region Data Source Time period Total deaths Rate of fatal venom anaphylaxis (per million/year) Age Gender predominance Leading causal insects Risk factors identified Authors
Australia Australian Bureau of Statistics and National Coronial Information System (NCIS) 1997-2013 324 (119 with known cause)
41 (13%) insect
X23, X25
0.09 Median 50 (range 19-79) 90% male Honeybee 73%
Ants 9%
Ticks 9%
Wasp 6%
Age
Male sex
Cardiovascular disease 45%
Upright posture 30%
Known venom allergy 48%
Squeezing tick bites associated with death in all tick cases
Mullins et al 201611
Canada (Ontario) Ontario Coroner's database 1986-2011 92 total
30 (33%) insect
Coroner reports searched; ICD codes not used.
0.1 Mean 54 (range 25 to 77) 80% male Not stated Age
Male sex
Known venom allergy in 11 of 21 (52%) cases where this information was available
Xu et al 201412
United Kingdom National fatal anaphylaxis registry 1992-2008 479 total
92 (19%) insect X23
0.09 Mean 59 (95% CI 56-63) Not stated Not stated Not stated Turner et al 201514
United States 3 national databases (NIS, NEDS, MCDD) 1999-2009 2229 total
295 (13%) insect X23
0.09 Not stated Not stated Not stated Not stated Ma et al 20142
United States National Center for Health Statistics MCDD 1999-2010 2458 total
374 (15%) insect
X23, X25, T63.4
0.17 in Southern states
0.11 to 0.13 in other areas
Median 52 y 80% male
88% white
Not stated Age
White race
Male sex
Jerschow et al 20146

ICD, International Classification of Diseases; MCDD, National Center for Health Statistics' Multiple Cause of Death Data; NCIS, Australian National Coronial Information System; NEDS, Nationwide Emergency Department Sample, from the Healthcare Cost and Utilization Project; NIS, Nationwide Inpatient Sample, from the Healthcare Cost and Utilization Project.