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. Author manuscript; available in PMC: 2017 Nov 8.
Published in final edited form as: Oncogene. 2017 May 8;36(36):5189–5198. doi: 10.1038/onc.2017.140

Figure 8. Effect of inhibitor of TGF-β receptors SB-431542 on cancer growth and angiogenesis.

Figure 8

In the experiment similar to those described in Fig. 7, 4.2 mg/kg SB-431542 in 0.1 ml of PBS or PBS alone was injected IP daily 30 min before the injection of TGF-β1. A: EMT6 tumor weight and representative tumors, n=10, ***p<0.005, *****p<0.00005. B: Levels of CD31 in tumors, IHC, n=10. C: Levels of NG2 in tumors, IHC, n=10. D: Levels of phospho-SMAD3 in tumors, IHC, n=10. E: Levels of TSP-4 in tumors, IHC, n=10.