Table 6. Detection of genes related to COX-2-Wnt/β-catenin pathway by PCR (X±S).
Group | GSK3β | AKT | VEGF | COX2 | β-catenin |
---|---|---|---|---|---|
Control | 1.00±0.10 | 1.00±0.08 | 1.00±0.10 | 1.00±0.08 | 1.00±0.06 |
PGE2 | 2.50±0.06 | 3.05±0.11 | 3.00±0.10 | 3.04±0.07 | 3.09±0.06 |
PGE2+TF(L) | 2.35±0.02Δ | 2.04±0.08Δ* | 2.10±0.11Δ* | 2.06±0.07Δ* | 2.02±0.09Δ* |
PGE2+TF(M) | 2.06±0.05Δ* | 1.03±0.08** | 0.98±0.05Δ** | 0.99±0.05** | 0.96±0.10** |
PGE2+TF(H) | 1.50±0.06Δ** | 0.63±0.04Δ** | 0.72±0.07ΔΔ** | 0.76±0.10Δ** | 0.76±0.11Δ** |
PGE2+AH6809 | 1.21±0.09 | 0.85±0.04 | 1.15±0.08 | 1.05±0.09 | 1.08±0.09 |
PGE2+Butaprost | 3.05±0.08 | 3.61±0.09 | 4.14±0.10 | 4.05±0.02 | 3.54±0.04 |
PGE2+Butaprost+TF(H) | 2.00±0.10## | 2.59±0.06## | 2.46±0.11## | 2.42±0.11## | 0.99±0.11## |
Compared with PGE2 group: * P<0.05; Compared with PGE2 group: **P<0.01
Compared with PGE2+AH6809 group: ΔP<0.05; Compared with PGE2+AH6809 group: ΔΔP<0.01
Compared with PGE2+Butaprost group: #P<0.05; Compared with PGE2+Butaprost group: ##P<0.01