Table 4. Multivariate analyses.

A
Parameter	HR	95% confidence interval		p-Value
		min	max
pT category	1.397	0.98	1.99	0.064
Lymph node metastasis	1.942	1.199	3.147	0.007
Grading	1.046	0.634	1.724	0.86
Age	4.093	2.418	6.929	0.001
LC3B dot-like staining	0.599	0.376	0.954	0.031
B
Parameter	HR	95% confidence interval		p-Value
		min	max
pT category	1.355	0.95	1.933	0.094
Lymph node metastasis	2.088	1.284	3.396	0.003
Grading	1.071	0.645	1.777	0.792
Age	4.084	2.409	6.921	0.001
p62 dot-like/cytoplasmic	0.507	0.285	0.902	0.021
C
Parameter	HR	95% confidence interval		p-Value
		min	max
pT category	1.408	0.983	2.016	0.062
Lymph node metastasis	1.87	1.151	3.037	0.011
Grading	1.058	0.641	1.749	0.825
Age	4.024	2.374	6.82	0.001
LC3B dot-like/p62 dot-like-cytoplasmic	0.751	0.607	0.928	0.008

A) model including LC3B dot-like immunohistochemical staining; B) model including p62 dot-like-cytoplasmic immunohistochemical staining; C) model including the combination of LC3B dot-like/p62 dot-like-cytoplasmic immunohistochemical staining.