Skip to main content
. 2017 May 30;8(33):54747–54763. doi: 10.18632/oncotarget.18287

Table 1. Time courses of transthoracic echocardiographic findings among five groups.

Variables Group 1 (n=6) Group 2 (n=6) Group 3 (n=6) Group 4 (n=6) Group 5 (n=6) p-value
Day 0
 LVEDd (mm) 34.91 ± 6.81 32.36 ± 5.0 34.0 ± 3.85 33.55 ± 7.0 35.90 ± 3.72 0.712
 LVESd (mm) 21.95 ± 4.92 20.76 ± 3.89 21.59 ± 1.70 20.68 ± 5.10 23.11 ± 2.87 0.531
 LVEF (%) 68.58 ± 3.67 67.04 ± 3.76 66.92 ± 3.69 67.39 ± 4.15 66.18 ± 2.96 0.882
Day 44*
 LVEDd (mm) 34.41 ± 4.82a 39.22 ± 2.31b 39.96 ± 3.43b 40.14 ± 3.24b 38.18 ± 3.12b <0.001
 LVESd (mm) 21.15 ± 2.92a 28.09 ± 1.61b 29.01 ± 1.62b 28.98 ± 2.08b 28.31 ± 1.96b <0.001
 LVEF (%) 67.86 ± 3.67a 55.36 ± 1.88b 55.26 ± 4.76b 57.84 ± 5.98b 57.05 ± 2.80b <0.001
Day 90†
 LVEDd (mm) 35.56 ± 2.17a 41.01 ± 5.18b 40.78 ± 6.61b 41.85 ± 3.46b 38.92 ± 5.10b <0.01
 LVESd (mm) 22.70 ± 1.89a 30.82 ± 3.44b 30.10 ± 4.43b 31.39 ± 2.37b 28.18 ± 3.50b <0.001
 LVEF (%) 66.82 ± 3.29a 50.27 ± 2.15b 51.47 ± 4.13b 50.77 ± 4.35b 51.96 ± 4.09b <0.001
Day 180
 LVEDd (mm) 36.26 ± 2.47a 45.59 ± 2.62b 45.43 ± 4.97b 45.05 ± 2.76b 46.23 ± 3.41b <0.0001
 LVESd (mm) 23.21 ± 2.02a 35.19 ± 4.43b 36.38 ± 4.46b 31.46 ± 1.61c 32.17 ± 1.45c <0.0001
 LVEF (%) 66.27 ± 3.72a 45.03 ± 9.59b 40.60 ± 5.05c 59.61 ± 3.93d 56.41 ± 2.79e <0.0001

Data are expressed as mean ± SD or (%).

Group 1 = sham-operated control; group 2 = left ventricular ischemia (LVIs) by ameroid constrictor applied to left anterior descending artery; group 3 = LVIs + chronic kidney disease (CKD) by right nephrectomy and half (1/2) of the left renal artery ligation (i.e., LVIs + CKD); group 4 = LVIs + extracorporeal shock wave (ECSW); group 5 = LVIs + CKD + ECSW.

* indicated the timing was 44 days after CKD induction.

† indicated the ECSW was applied to groups 4 and 5 by day 90 after CKD induction.

LVEDd: left ventricular end-diastolic dimension; LVESd: left ventricular end-systolic dimension; LVEF: left ventricular ejection fraction.

Letters (a, b, c, d, e) indicate significant difference (at 0.05 level) by Tukey multiple comparison procedure.