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(A) Scrambled control and Hsp27-KD HepJ5 cells were inoculated subcutaneously into nude mice. The sizes of the tumors were monitored weekly, and the animals were sacrificed at day 28. (B–C) The weights of Hsp27-KD tumors were markedly lower than those of scrambled tumors. (D) The body weights of the scrambled control group and Hsp-27KD group were similar. (E) IHC staining indicated decreased Hsp27 staining in Hsp27-KD tumors.
