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. 2017 Jun 27;8(33):55116–55134. doi: 10.18632/oncotarget.18664

Figure 1. miR-331-3p expression is reduced in PCa tissue relative to a paired non-malignant adjacent tissue (NAT).

Figure 1

(A) Taqman qRT-PCR detection of miR-331-3p in tumor samples (red bars) relative to a matched non-malignant control sample (green bars) in a pilot cohort study. (B) Taqman qRT-PCR detection of miR-331-3p in tumor samples relative to a matched non-malignant control sample in a larger patient cohort study. miR-331-3p expression is colour indicated, where red is significantly increased by > 1.5 fold, green is significantly decreased by > 1.5 fold and grey is unchanged. (C) miR-331-3p expression is significantly downregulated in prostate tumors. Pie graph representation of miR-331-3p expression across a large cohort study of 46 patient tumor samples with matched non-malignant control samples. The smaller circle indicates the 25 samples in which miR-331-3p is downregulated, with significant absolute fold changes (<1.5 fold) visually annotated by difference in size and colour gradient within this downregulated subset. (D) miR-331-3p expression across all tumor samples compared to non-malignant matched controls in a 46 patients cohort.