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. 2017 Jun 27;8(33):55116–55134. doi: 10.18632/oncotarget.18664

Figure 6. The effects of miR-331-3p and AKi-II pre-treatment of PCa cells on 22Rv1 xenograft growth.

Figure 6

(A) miR-NC and miR-331-3p (+/- AKi-II; 10μM) xenograft NSG mice were monitored over a 33 day period for tumor size and volume. (B) Coronal and axial images from Day 33 representative mice from miR-NC and miR-3313p (+/- AKi--II; 10μM) xenograft groups. Tumor area is highlighted by red dash circle. (C) End point Kaplan-Meier survival curve of 22Rv1 xenograft mice +/- miR-NC/ miR-331-3p /AKi-II; 10μM). Log-rank (Mantel-Cox) Test; ***p<0.0005. Logrank test for Trend p<0.0011.