Table 18. Summary of HIEPC-related procedures in different PC institutions or countries (published researches).
Country /No. Institutions |
Major Institutions | No. patients | Mode | HIPEC-MMC alone | HIPEC-MMC+DDP | HIPEC-L-OHP alone | HIPEC-other | Temperature (°C) |
Duration (min) |
---|---|---|---|---|---|---|---|---|---|
China, 1 | Zhongnan Hospital of Wuhan University [39] | ||||||||
Subtotal | 62 | O | MMC (30 mg) + DDP (120 mg) | 43.0±0.5 | 90 | ||||
Norway, 1 | Norwegian Radium Hospital [103] | ||||||||
Subtotal | 109 | O/C | 35 mg/m2 | 41.4 (39.5-42.1) | 90 | ||||
Denmark, 1 | Aarhus University Hospital [60, 75] | ||||||||
Subtotal | 53 | O | 35 mg/m2 | 41-42.5 | 90 | ||||
Germany, 1 | University of Wuerzburg Medical Centre [15, 29, 72] | ||||||||
Subtotal | >11 | O | 10-20 mg/m2 | Y | 42 /40-43 | 90 /30 | |||
Israel. 1 | Tel Aviv Medical Center [13] | ||||||||
Subtotal | 25 | O/C | Y | Y | Y | MMC+CPT-11, 5-FU | 40-43 | 30-90 | |
Japan, 1 | Shizuoka Cancer Centre [13] | ||||||||
Subtotal | 25 | O/C | Y | Y | Y | MMC+CPT-11, 5-FU | 40-43 | 30-90 | |
Mexico, 1 | Instituto Jalisciense de Cancerologia [29, 72] | ||||||||
Subtotal | ? | O/C | Y | Y | 40-43 | 30-120 | |||
Serbia and Montenegro, 1 | First Surgical University Hospital, Clinical Center of Serbia [61] | ||||||||
Subtotal | 18 | C | 10 or 12.5 mg/m2 | 42 | 120 |
Note: C: closed abdomen technique for HIPEC; O: open abdomen technique for HIPEC; Y: yes; MMC: mitomycin C; DDP: cisplatin; 5-FU: fluorouracil; L-OHP: oxaliplatin; CPT-11: irinotecan