Table 19. Summary of HIEPC-related procedures in different PC institutions or countries (published researches).
| Country /No. Institutions |
Major Institutions | No. patients | Mode | HIPEC-MMC alone | HIPEC-MMC+DDP | HIPEC-L-OHP alone | HIPEC-other | Temperature (°C) |
Duration (min) |
|---|---|---|---|---|---|---|---|---|---|
| Serbia, 1 | Institute for Oncology and Radiology of Serbia [70] | ||||||||
| Subtotal | 61 | C | 410 mg/m2 | 41 | 30-60 | ||||
| Singapore, 1 | National Cancer Centre Singapore [79, 81] | ||||||||
| Subtotal | 63 | C | Y | 42 | 60 | ||||
| Sweden, 1 | Akademiska Sjukhuset, Uppsala University Hospital [83] | ||||||||
| Subtotal | 38 | O | 460 mg/m2 | 42-44 | 30 | ||||
| Total | 73 | ≈6,500 | O (n = 63) C (n = 51) |
n = 64 30-50 mg/m2 10-12.5 mg/m2 35 mg/m2 10-20 mg/m2 |
n = 24 30-50 mg/m2 + 50-100 mg/m2 |
n = 43 460 mg/m2 360-460 mg/m2 |
MMC+CPT-11, 5-FU L-OHP + CPT-11 MMC + CPT-11 |
41.5 (40-43) /43 (40-43) | 90 (60-90) / 60 |
Note: C: closed abdomen technique for HIPEC; O: open abdomen technique for HIPEC; Y: yes; MMC: mitomycin C; DDP: cisplatin; 5-FU: fluorouracil; L-OHP: oxaliplatin; CPT-11: irinotecan