Table 4.

Diagnostic and overall accuracy of [TIMP-2]·[IGFBP7] for AKI compared with gold standard AKIN classification

[TIMP-2]·[IGFBP7] cut-off value ((ng/mL)2/1000)	Se %	95% CI	Sp %	95% CI	AUC	95% CI
0.3—to predict AKI	81.6	78.2–85.0	59.2	54.9–63.5	0.80	0.71–0.89
0.4—to predict AKI	73.5	69.7–77.5	71.4	67.4–75.4
0.8—to predict AKIN ≥ 2	72.0	68.1–75.9	78.1	74.6–81.8	0.81	0.70–0.91
2.0—to predict AKIN ≥ 2	48.0	43.6–52.4	90.4	87.8–93.0

AUC area under curve of ROC analysis; CI confidence interval; Se sensitivity; Sp specificity