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. 2017 Sep 7;7:10888. doi: 10.1038/s41598-017-09971-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Continuous transcutaneous tracing of enterally administered MB-402 and MB-301. MB-402: MB-301 ratios (Y-axis) were determined over time (X-axis) after fluorophore gavage. One day earlier, two rats were challenged with high-dose indomethacin (green lines and circles) and two rats were challenged with vehicle alone (red lines and circles). Measurements are truncated for one control rat because it died an hour before the experiment ended.