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. 2017 Sep 7;7:10833. doi: 10.1038/s41598-017-11398-4

Table 1.

General characteristic of the included studies.

First Author publication year study design types of ARDs disease duration (mean ± SD) number age (mean ± SD) sex (M/F) NOS scale
Patint Control Patient Control Patient Control
A. Balkarl 2016 retrospective study BD N 120 79 37.83 ± 11.86 37.63 ± 10.82 72/48 46/33 8
Acikgoz, N. 2010 retrospective study BD 9.1 ± 5.1 60 40 40.5 ± 12.9 41.3 ± 6.8 31/29 18/22 8
Boyraz, I. 2014 retrospective study AS N 105 50 46.83 ± 14.94 41.02 ± 17.37 78/27 28/22 8
Boyraz, I. 2016 retrospective study AS 8.8 ± 8 30 25 38.6 ± 8.3 37.1 ± 9.4 19/11 16/9 8
Bozan, N. 2016 retrospective study AS 5.29 ± 5.09 30 35 32 ± 8 32 ± 6 18/12 22/13 7
Coskun, B. N. 2014 retrospective study AS 9.25 ± 8.37 35 38 38.91 ± 11.90 37.36 ± 6.90 26/9 26/12 8
Gokmen, F. 2015 retrospective study AS N 96 81 43.8 ± 12.9 46.5 ± 11.2 65/31 47/34 6
Li, L. 2015 retrospective study SLE N 59 149 29.47 ± 12.63 28.44 ± 4.42 4/55 17/132 8
Mercan, R. 2016 retrospective study AS N 140 117 37.1 ± 9.8 37.2 ± 13.2 79/61 42/75 8
RA N 136 117 51.7 ± 13.5 37.2 ± 13.2 15/121 42/75
Oehadian, A. 2013 cross sectional study SLE N 21 30 28.5 ± 41.08 28.5 ± 60.42 0/21 10/20 8
Ozturk, C. 2015 retrospective study BD 9.26 ± 7.09 65 62 36.30 ± 10.98 34.16 ± 9.33 38/27 31/31 8
Peng, Y. F. 2014 retrospective study AS N 44 113 35.98 ± 16.24 33.87 ± 7.88 30/14 82/31 8
Rifaioglu, E. N. 2014 retrospective study BD N 65 136 37.7 ± 12.3 38.8 ± 11.3 38/17 56/80 8
Safak, S. 2014 retrospective study SLE N 44 44 42 ± 16 41 ± 17 11/33 9/35 8
Soydinc, S. 2014 retrospective study SSc N 76 45 50.44 ± 13.21 46.52 ± 13.16 14/62 11/34 8
Wu, Y. 2016 retrospective study SLE N 116 136 27.81 ± 32.73 28.5 ± 12.75 19/97 25/111 8
Yolbas, S. 2016 retrospective study BD 6.9 ± 5.9 53 55 37.4 ± 10.9 45.1 ± 13 20/33 11/44 8
RA 8.2 ± 7.9 91 55 51.7 ± 14.5 45.1 ± 13 15/76 11/44
SLE 4.6 ± 5.2 51 55 33 ± 9.6 45.1 ± 13 4/47 11/44
Zengin, O. 2016 retrospective study RA N 317 104 44.33 ± 10.41 43.16 ± 11.69 206/111 68/36 7

F: female; M: male; RA: rheumatoid arthritis; SLE: systemic lupus erythematosus; BD: Behçet’s Disease; AS: ankylosing spongdylitis; SD: standard deviation; NOS: Newcastle-Ottawa scale.