Table 2.
In vitro fungicidal activity of the selected peptides L12P and L18R.
| Yeast strain | EC50* (95% confidence intervals) [mol/liter] × 10−6 | |
|---|---|---|
| L12P | L18R | |
| Candida albicans SC5314 | 0.489 (0.445–0.538) | 0.443 (0.437–0.549) |
| C. albicans CA-6 | 0.556 (0.522–0.591) | 0.294 (0.292–0.296) |
| C. albicans SA40 | 0.537 (0.531–0.544) | 0.315 (0.271–0.366) |
| C. albicans AIDS68 | 0.501 (0.468–0.537) | 0.449 (0.435–0.463) |
| C. albicans UM4 | 0.627 (0.534–0.736) | 0.454 (0.414–0.499) |
| C. glabrata OMNI32 | 0.546 (0.520–0.574) | 0.356 (0.339–0.373) |
| Cryptococcus neoformans 6995 | 0.364 (0.353–0.375) | 0.188 (0.180–0.196) |
| Malassezia furfur 101 | 0.658 (0.574–0.754) | 0.527 (0.472–0.586) |
*EC50, half maximal effective concentration, calculated by nonlinear regression analysis using Graph Pad Prism 4.01 software.