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. 2017 Sep 7;7:10770. doi: 10.1038/s41598-017-11503-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Quantitative single cell analysis based on time-lapse fluorescent movies of WT M. smegmatis vs. the msm1946::Tn mutant during the 72 hours of INH 50 µg/ml exposure in the single cell microfluidic device. First row demonstrates the cumulative behavior of the cells, the second row demonstrates number of normalized lysis, and the last row illustrates number of normalized division events.