Table 2.
List of cell-specific characteristics which are used to characterise cells in this model.
Parameter | Description |
---|---|
Genome Size | Length of haploid genome in GBP |
Chromosome Number | Total number of chromosomes in cell |
NHEJ Repair Capacity | Availability of NHEJ repair pathway |
HR Repair Capacity | Availability of HR pathway |
G1 Arrest Function | Availability of G1/S phase damage arrest checkpoint |
Cell Cycle Phase | Cell cycle phase (Single specified phase or asynchronous) |
All parameters are obtained from the literature and used to predict cellular radiosensitivity without free fitting parameters.