Table 1.
Patient characteristics where septic population is determined by clinical adjudication labels. Blood culture results and SIRS criteria measurements reported were taken at the time of the biomarker measurement.
| Characteristic | Early to Peak Phase Sepsis Population (N = 76) | Non-septic and Recovery Phase SepsisPopulation (N = 368) | |
|---|---|---|---|
| Age, SD | 61, 19 | 61, 20 | |
| Gender | 47% male, 53% female | 56% male, 44% female | |
| Chronic Conditions | Cancer | 20% | 17% |
| Diabetes | 29% | 19% | |
| Chronic Kidney Disease | 9% | 9% | |
| COPD | 12% | 10% | |
| Asthma | 1% | 1% | |
| Infection (i.e pneumonia, bronchitis, meningitis) | 89% | 67% | |
| Most common infections | Pneumonia | 28% | 23% |
| Cellulitis | 14% | 19% | |
| UTI | 41% | 19% | |
| GI infections | 11% | 5% | |
| Positive Blood Culture | 38% | 22% | |
| SIRS (at least 2/4 criteria) | 93% | 64% | |
| SIRS (exactly 2/4 criteria) | 25% | 33% | |
| SIRS (exactly 3/4 criteria) | 39% | 25% | |
| SIRS (exactly 4/4 criteria) | 29% | 8% | |
| Infection + SIRS (at least 2/4 criteria) | 79% | 42% | |
| Infection + SIRS (exactly 2/4 criteria) | 22% | 22% | |
| Infection + SIRS (exactly 3/4 criteria) | 36% | 16% | |
| Infection + SIRS (exactly 4/4 criteria) | 21% | 4% | |
| SOFA score, SD | 3.77, 3.39 | 2.17, 2.45 | |
| qSOFA score, SD | 1.46, .92 | 1.07, .94 | |