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. 2017 Sep 7;7:10908. doi: 10.1038/s41598-017-10716-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The distinct proliferation potential of three liver cell lines. (A) The proliferation of three liver cell lines under the same initial cell number and culture condition from day 1 to day 5. (B) The morphology of cultured three cell lines at day 5 under 100X microscope. (C) The results of proliferation assay using nude mice model. (D) The western blot results of phosphorylated sites T46 of EIF4IBP1 and S141 of PAK2, the middle graph is the statistical results of western blot based on densitometric analysis. The right bar charts compare the relative abundance of phosphorylated PAK2 and EIF4BP1 in QGY and Hep3B to L02 by MS/MS method.