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. 2017 Sep 7;7:10801. doi: 10.1038/s41598-017-09790-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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TGF-β1 and LOX expression during post-MI remodeling. (A) Protein expression by Western blotting of TGF-β1. (B) TGF-β1 concentration measured in cytokine array. (C) TGF-β1 secretion by cultured Fb cells derived from SHAM and MI. (D) LOX expression in tissue from the adjacent and remote myocardium of SHAM and MI. (E) LOX activity in tissue, (F) Lox activity in cultured Fb cells derived from SHAM and MI. *p < 0.05, **p < 0.01. (*p < 0.05: **p < 0.01: *** < 0.001). (2-way ANOVA with Bonferroni post hoc test for 6A, B, D, E;1-way ANOVA with Bonferroni post hoc test for 6 C, F)