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. Author manuscript; available in PMC: 2017 Sep 8.
Published in final edited form as: JACC Cardiovasc Imaging. 2016 May 25;9(8):950–961. doi: 10.1016/j.jcmg.2016.01.020

Figure 6. Plaque targeting of 89Zr-HDL nanoparticles in rabbits with atherosclerosis.

Figure 6

A) Comparison between SUVs measured from PET/CT images and radioactivity concentration in aortas of rabbits with atherosclerosis and wild type controls at 5 days p.i. of 89Zr-AI-HDL (top) and 89Zr-PL-HDL (bottom) (n = 4 per group). B) Autoradiography and NIRF images of whole aortas from rabbits with atherosclerosis and wild type controls at 5 days post administration of 89Zr-AI-HDL and Cy5.5-HDL (top) and 89Zr-PL-HDL and Cy5.5-HDL (bottom). C) Comparison between NIRF intensity (total radiant efficiency, in µW/cm2) and radioactivity concentration in aortas of rabbits with atherosclerosis and wild type controls at 5 days post administration of 89Zr-AI-HDL and Cy5.5-HDL (top) and 89Zr-PL-HDL and Cy5.5-HDL (bottom) (n = 4 per group). * P < 0.05.