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. 2017 Jul 10;38(9):1205–1235. doi: 10.1038/aps.2017.28

Table 6. Summary of anti-aggregation agents for the treatment of Alzheimer's disease.

Name Targets Effects Ref
Apomorphine Prevents Aβ aggregation Reduces cellular toxicity 299
Hormone melatonin Inhibits Aβ aggregation Reverts amyloid deposition 300
Cannabinoid HU-210 Blocks microglial activation Prevents Aβ-promoted inflammation 296
Tannic Acid Binds Aβ fibrils Inhibits Aβ aggregation and cytotoxicity 301
LJW0F2 Polysaccharide that blocks Aβ fibril formation Reduces neurotoxicity 302
EGb761 Inhibits Aβ aggregation Reduces neurotoxicity 303
Isoliquiritigenin Inhibits Aβ aggregation Reduces neurotoxicity 304
Protocatechuic acid Inhibits Aβ aggregation Reduces neurotoxicity 304
Atractylenolide III Inhibits Aβ aggregation Reduces neurotoxicity 304
Chlorogenic acid Inhibits Aβ aggregation Reduces neurotoxicity 304
Euphorbiafactor L3 Inhibits Aβ aggregation Reduces neurotoxicity 304
Euphorbiafactor L2 Inhibits Aβ aggregation Reduces neurotoxicity 304
Ganoderic acid D Inhibits Aβ aggregation Reduces neurotoxicity 304
Ganoderic acid DM Inhibits Aβ aggregation Reduces neurotoxicity 304
Substituted Bisphenol A Derivatives Inhibit Aβ aggregation Inhibit neurotoxicity and increase cell viability 305