Table 6. Summary of anti-aggregation agents for the treatment of Alzheimer's disease.
Name | Targets | Effects | Ref |
---|---|---|---|
Apomorphine | Prevents Aβ aggregation | Reduces cellular toxicity | 299 |
Hormone melatonin | Inhibits Aβ aggregation | Reverts amyloid deposition | 300 |
Cannabinoid HU-210 | Blocks microglial activation | Prevents Aβ-promoted inflammation | 296 |
Tannic Acid | Binds Aβ fibrils | Inhibits Aβ aggregation and cytotoxicity | 301 |
LJW0F2 | Polysaccharide that blocks Aβ fibril formation | Reduces neurotoxicity | 302 |
EGb761 | Inhibits Aβ aggregation | Reduces neurotoxicity | 303 |
Isoliquiritigenin | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Protocatechuic acid | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Atractylenolide III | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Chlorogenic acid | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Euphorbiafactor L3 | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Euphorbiafactor L2 | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Ganoderic acid D | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Ganoderic acid DM | Inhibits Aβ aggregation | Reduces neurotoxicity | 304 |
Substituted Bisphenol A Derivatives | Inhibit Aβ aggregation | Inhibit neurotoxicity and increase cell viability | 305 |