Table 1. Echocardiographic parameters of rats treated with ISO and C33(S).
| Parameters | control | ISO | C33-H | C33-M | C33-L |
|---|---|---|---|---|---|
| LVAW-d (mm) | 1.34±0.02 | 1.65±0.01 | 1.56±0.06 | 1.81±0.13## | 1.63±0.37 |
| LVAW-s (mm) | 2.52±0.22 | 2.26±0.20 | 2.41±0.05 | 2.94±0.02## | 2.21±0.58 |
| LVPW-d (mm) | 1.50±0.05 | 1.51±0.10 | 1.59±0.10 | 1.68±0.28 | 1.85±0.14 |
| LVPW-s (mm) | 2.68±0.21 | 2.43±0.63 | 2.99±0.01# | 3.45±0.36## | 3.05±0.33e |
| LVID-d (mm) | 6.99±0.58 | 7.93±0.29* | 7.61±0.29# | 7.11±0.24## | 7.06±1.20 |
| LVID-s (mm) | 3.81±0.85 | 5.37±0.30** | 4.30±0.46# | 3.21±0.03## | 4.01±1.23 |
| EF (%) | 75.49±8.37 | 49.17±4.20* | 72.97±4.64# | 84.29±1.56## | 73.41±9.37# |
| FS (%) | 45.85±7.62 | 32.18±6.28* | 43.55±3.98# | 54.79±1.95## | 43.98±7.96# |
| CO (mL/min) | 64.88±4.50 | 48.97±2.11* | 60.01±9.11## | 69.40±11.63# | 58.08±8.47 |
| HR (BPM) | 345.17±25.93 | 297.04±8.88 | 305.53±14.68 | 306.94±22.90 | 304.73±23.78 |
Abbreviations: LVAW, left ventricular anterior wall thickness; LVPW, left ventricular posterior wall thickness; LVID, left ventricular internal diameter; EF, ejection fraction, FS, fractional shortening; SV, stroke Volume; CO, cardiac output; HR: heart rate; -s, systolic; -d, diastolic. ISO, isoproterenol stimulated for 3 weeks; C33-H, C33(S) 9 mg·kg−1·d−1; C33-M, C33(S) 3 mg·kg−1·d−1; C33-L, C33(S) 1 mg·kg−1·d−1. Data were presented as mean±standard error of the mean.
*P<0.05,
**P<0.01 vs control group.
#P<0.05,
##P<0.01 vs ISO group. n=3–6.