Figure 3.

HPV16-detect assay tracked presence of residual disease with ¹⁸F-FDG PET-CT at corresponding time points. HPV DNA levels decreased in response to treatment at 6 weeks, but increased significantly at 12 weeks, which corresponded to presence of liver metastases on ¹⁸F-FDG PET-CT. HPV DNA levels decreased post-liver resection, however never dropped below the threshold. ¹⁸F-FDG PET-CT 8 months following liver surgery revealed disease relapse in cervical lymph nodes. CRT=chemo-radiotherapy; PA=post-assessment; post-IC=post-induction chemotherapy. A full colour version of this figure is available at the British Journal of Cancer journal online.