Table 2.
Characteristics of cases with severe late-onset restrictive lung defect developed after hematopoietic stem cell transplantation
| Case | Months from HSCT to Dx of LONIPCs | Months of survival from Dx of LONIPCs | Months from HSCT to respiratory symptoms | PPFE pattern | Unclassifiable IP pattern | Airway-predominant pattern (Centrilobular nodules with BO) | Bronchiectasis | BO | Pneumothorax | Pneumomediastinum |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 90 | 42 | 103 | + | – | – | + | – | – | – |
| 2 | 26 | >84 | 67 | + | – | – | + | – | + | – |
| 3 | 41 | 132 | 62 | + | – | – | + | – | + | – |
| 4 | 40 | >33 | 54 | + | – | – | – | – | + | – |
| 5 | 109 | 60 | 109 | + | – | – | – | – | – | – |
| 6 | 60 | 16 | 64 | – | + | – | – | – | + | – |
| 7 | 16 | 3 | 16 | – | + | – | – | + | + | – |
| 8 | 22 | 44 | 19 | – | – | + | – | + | – | – |
| 9 | 50 | >80 | 69 | – | – | + | + | + | – | – |
| 10 | 126 | 10 | 124 | – | – | + | – | + | – | – |
| 11 | 36 | >117 | 30 | + | – | – | – | + | – | – |
| 12 | 48 | 25 | 54 | + | – | – | + | – | + | + |
HSCT hematopoietic stem cell transplantation, Dx diagnosis, LONIPCs late-onset noninfectious pulmonary complications, PPFE pleuroparenchymal fibroelastosis, IP interstitial pneumonia, BO bronchiolitis