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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Mesoporous silica nanoparticle (MSN)-doxorubicin (DOX) via hydrazone bond on the surface. The acid-labile bond is cleaved at acidic pH, and the drug is released only in the desired area.