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. 2017 May 8;4(2):42. doi: 10.3390/bioengineering4020042

Figure 6.

Figure 6

Inhibition of cancer cell line proliferation by hTM and CM IgA2 antibodies. Proliferation within 4–5 days relative to a control grown in medium without antibody was calculated. hTM IgA2 (a) and CM IgA2 (b) antibodies inhibited the proliferation of SK-BR-3 (Her2 +++) and A-431 (EGFR ++) target cells, respectively. For SK-BR-3 and A-431, hOM IgA2 antibody served as the irrelevant matched isotype negative control. One representative out of three independent experiments is shown. Mean values of duplicates are shown. Antigen binding sites were determined using IgG antibodies; antigen binding sites: +, 1 × 104 to 1 × 105; ++, 1 × 105 to 5 × 105; +++, >5 × 105.