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hOM anti-CD20 IgA2 antibody binds Raji target cells and mediates B cell depletion. (a) Concentration-dependent binding of hOM IgA2 to Raji target cells by flow cytometry. (b) Whole blood was used as a source for target and effector cells. Mean values of duplicates and one out of two independent experiments are shown. hOM IgA2 showed at least comparable maximal B cell depletion like commercially available Mabthera anti-CD20 IgG control.
