Table 1.
Overview of the targets, isotypes and production levels of the generated IgA antibodies.
| Name (Abbreviation) | Target | Variants Generated | Titer (mg/L) |
|---|---|---|---|
| PankoMab (hPM) | Tumor-associated mucin 1 (TA-MUC1) | IgA1 | 41.8 |
| IgA2 | 4.0 * | ||
| TrasGEX (hTM) | Epidermal growth factor receptor 2 (Her2) | IgA2 | 55.8 |
| IgA2J | 41.5 | ||
| CetuGEX (CM) | Epidermal growth factor receptor 1 (EGFR) | IgA2 | 6.5 |
| IgA2J | 9.8 | ||
| KaroMab (hKM) | Thomsen-Friedenreich (TF) antigen, core 1 | IgA2 | 24.7 |
| ObiGEX (hOM) | B-lymphocyte antigen CD20 | IgA2 | 15.3 |
Names were introduced for IgG antibodies; mean titer of 2–5 clones in supernatants of spinner cultures upon harvest; * one selected clone.