Table 3.
Variable | Study group | P | ||
---|---|---|---|---|
0.75-d3 (N = 20) | 0.50-d1 + 0.25-d3 (N = 21) | 0.25-d1,2,3 (N = 20) | ||
Asexual parasitaemia [parasites/µL] by microscopy median (IQR); geometric mean | 968 (274–2,909); 1,119 | 2,620 (918–3,974); 1,896 | 686 (70–1,646); 544 | 0.071 (KW) |
Asexual parasitaemia [DNA copies/µL] by qPCR median (IQR); geometric mean | 10,377 (1,122–12,574); 7,052 | 22,815 (14,488–30,019); 19,799 | 10,561 (6,263–10,561); 4,147 | 0.002 (KW) |
Gametocyte prevalence by microscopy % (n) [CI 95%] | 10 (2) [1–32] | 5 (1) [0.1–24] | 0 (0) [0–17] | 0.352 (χ2) |
Gametocyte prevalence by qPCR % (n) [CI 95%] | 60 (12) [36–81] | 24 (5) [8–47] | 50 (10) [27–73] | 0.054 (χ2) |
Gametocytes density by qPCR [cDNA copies/µL] median (IQR); geometric mean | 12 (0–202); 55 | 0 (0–2); 166 | 2 (0–16); 19 | 0.117 (KW) |
qPCR = quantitative polymerase chain reaction; IQR = interquartile range; KW = Kruskal–Wallis. CI 95% = exact binomial confidence interval of 95%, geometric mean was calculated excluding negative samples.
Bold values indicate a P value < 0.05.