Table 5.

Net relative change in gametocytemia per study group

Prevalence
Treatment	Prevalence (%)			Net relative change (%)*
	Day 1	Day 4	Day 7	Days 1–4	Days 1–7	Days 4–7
0.75-d3	60	35	15	−42	−75	−57
0.50-d1 + 0.25-d3	24	19	40	−21	+66	+110
0.25-d1,2,3	50	25	50	−50	0	+100
Total	44	26	35	−41	−20	+35

Density
Treatment	Density (geometric mean, cDNA copies/µL)			Net relative change (%)*
	Day 1	Day 4	Day 7	Days 1–4	Days 1–7	Days 4–7
0.75-d3	55	17	33	−69	−40	+94
0.50-d1 + 0.25-d3	166	15	14	−91	−91	−7
0.25-d1,2,3	19	24	62	+26	+226	+158
Total	56	18	30	−68	−46	+66

^*Net relative change indicates the proportion of increase (positive value) or decrease (negative value) of gametocytemia (prevalence or density) over time with each scheme. These calculations were performed to obtain the net relative change of day 4 or 7 with respect to day 1: 100 − (prevalence or density on day 4 or 7 × 100/prevalence or density on day 1). Geometric mean was calculated excluding samples without gametocytes.