Table 3.
Association between pancreatic cancer and s-MICA levels stratified by sex, age, smoking status, alcohol consumption, and diabetes status,.
| Gender | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
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| Categories | Males | Females | ||||||||
|
| ||||||||||
| Concentration (pg/ml) | Cases | Controls | OR (95%CI) †† | Cases | Controls | OR(95%CI) †† | P-value for interaction | |||
| 2.0–32.0 | 21 | 95 | Reference | 16 | 68 | Reference | ||||
| 32.1–64.7 | 24 | 95 | 1.41 (0.78 – 2.56) | 20 | 62 | 1.49 (0.67 – 3.314) | ||||
| ≥64.7 | 43 | 71 | 3.39 (1.88 – 6.09) | 19 | 68 | 1.03 (0.454 – 2.345) | 0.1 | |||
|
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| Age | ||||||||||
|
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| Categories | Under 70 years old | Over 70 years old | ||||||||
|
| ||||||||||
| Concentration (pg/ml) | Cases | Controls | OR (95%CI) †† | Cases | Controls | OR(95%CI) †† | P-value for interaction | |||
|
| ||||||||||
| 2.0–32.0 | 20 | 96 | Reference | 17 | 67 | Reference | ||||
| 32.1–64.7 | 26 | 96 | 1.058 (0.525 – 2.13) | 18 | 61 | 1.28 (0.64 – 2.57) | ||||
| ≥64.7 | 36 | 66 | 2.27 (1.18 – 4.41) | 26 | 73 | 1.55 (0.80 – 2.98) | 0.07 | |||
|
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| Smoking Status | ||||||||||
|
| ||||||||||
| Categories | Never | Former | Current | |||||||
|
| ||||||||||
| Concentration (pg/ml) | Cases | Controls | OR (95%CI) ††† | Cases | Controls | OR (95%CI) ††† | Cases | Controls | OR (95%CI) ††† | P-value for interaction |
|
| ||||||||||
| 2.0–32.0 | 17 | 84 | Reference | 15 | 61 | Ref. | 6 | 17 | Ref. | |
| 32.1–64.7 | 16 | 68 | 1.58 (0.67 – 3.76) | 22 | 68 | 1.11 (0.48 – 2.56) | 8 | 22 | 0.44 (0.10 – 1.87) | |
| ≥64.7 | 23 | 57 | 2.12 (0.92 – 4.92) | 28 | 72 | 1.69 (0.8 – 3.59) | 8 | 10 | 1.49 (0.35 – 6.43) | 0.96 |
|
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| Alcohol | ||||||||||
|
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| Categories | 0 servings / week | 1–6 servings / week | ≥ 7 servings / week | |||||||
|
| ||||||||||
| Concentration (pg/ml) | Cases | Controls | OR (95%CI) †††† | Cases | Controls | OR (95%CI) †††† | Cases | Controls | OR (95%CI) †††† | P-value for interaction |
|
| ||||||||||
| 2.0–32.0 | 17 | 57 | Reference | 14 | 65 | Ref. | 7 | 45 | Reference | |
| 32.1–64.7 | 24 | 63 | 1.62 (0.74 – 3.57) | 9 | 64 | 0.74 (0.29 – 1.89) | 6 | 23 | 1.15 (0.27 – 4.78) | |
| ≥64.7 | 29 | 67 | 1.83 (0.85 – 3.95) | 26 | 52 | 1.88 (0.83 – 4.25) | 7 | 23 | 1.74 (0.45 – 6.69) | 0.82 |
|
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| Diabetes | ||||||||||
|
| ||||||||||
| Categories | Yes | No | ||||||||
|
| ||||||||||
| Concentration (pg/ml) | Cases | Controls | OR (95%CI) ††††† | Cases | Controls | OR(95%CI) †††††† | P-value for interaction | |||
|
| ||||||||||
| 2.0–32.0 | 6 | 9 | Reference | 31 | 153 | Reference | ||||
| 32.1–64.7 | 16 | 8 | 8.608 (1.57 – 47.24) | 28 | 150 | 1.03 (0.06 – 1.71) | ||||
| ≥64.7 | 25 | 20 | 5.22 (1.08 – 25.15) | 37 | 119 | 1.88 (1.14 – 3.10 ) | 0.03 | |||
Adjusted for age (modeled as a continuous variable), smoking status (never, former and current), alcohol consumption (no consumption, 1–6 servings per week and 7 or more servings per week) and diabetes (yes vs no).
Adjusted for sex, smoking status (never, former and current), alcohol consumption (no consumption, 1–6 servings per week and 7 or more servings per week) and diabetes (yes vs no).
Adjusted for sex, age (modeled as a continuous variable), alcohol consumption (no consumption, 1–6 servings per week and 7 or more servings per week) and diabetes (yes vs no).
Adjusted for sex, age (modeled as a continuous variable), smoking status (never, former and current), and diabetes (yes vs no).
Adjusted for sex, age (modeled as a continuous variable), smoking status (never, former and current), and alcohol consumption (no consumption, 1–6 servings per week and 7 or more servings per week).