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. 2017 Sep 1;10:4329–4338. doi: 10.2147/OTT.S141345

Figure 4.

Figure 4

Effect of SD1029 on PTTG1 and GADD45β mRNA levels in AtT20 cells.

Notes: Triplicate cell treatments were conducted, and the average of three independent experiments is shown. One-way ANOVA was conducted, followed by Fisher’s protected least significant difference post hoc test to determine differences between treatment means (*P<0.05 compared with control [C]). (A, C) Time-dependent effect of SD1029 on PTTG1 and GADD45β mRNA levels; cells were incubated with medium containing 10 µM SD1029. (B, D) Dose-dependent effects of SD1029 on PTTG1 and GADD45β mRNA levels; cells were incubated for 24 hours with medium containing between 100 nM and 10 µM SD1029.