Fig. 3.

Wy-14,643 strongly induces cell proliferation marker, BrdU, in the livers of both Ikkb^F/F and Ikkb^F/F-AlbCre mice. (A) Ikkb^F/F and Ikkb^F/F-AlbCre mice were treated with Wy-14,643 (0.1%, w/w) for 2 weeks. Liver samples were subjected to BrdU staining for evaluation of cell proliferation. Lipid droplets were stained with Oil Red O dye to check for the induction of lipogenesis in mice fed the Wy-14,643 diet. (B) The relative BrdU counts from (A) were measured using ImageJ program. ^***p<0.0001.