Table 2.

Patient data overview

Dose group (mg)	Patient no.	Fib-4 baseline	Plasma quercetin baseline (μg/L)	Plasma quercetin week 4 (μg/L)	% Change (baseline vs week 4)
					Plasma quercetin	ALT	AST	Viral load
250	1a	2.36	37.13	136.54	268%	−16%	−26%	−84%
	2a	2.34	123.14	131.76	7%	4%	−5%	−69%
	3	2.52	32.98	232.34	604%	−10%	−29%	−15%
500	4	1.89	121.57	861.78	609%	−13%	−9%	3%
	5	2.65	25.07	966.67	3756%	−4%	−58%	78%
	6	1.56	33.54	1515.81	4419%	−17%	−11%	−8%
1000	7	4.15	62.53	2895.74	4531%	41%	36%	59%
	8	1.31	51.26	405.52	691%	7%	7%	−39%
	9a	1.71	57.79	864.05	1395%	−9%	−5%	−31%
1400	10	1.88	76.16	559.79	635%	−16%	−11%	16%
	11	2.17	68.28	830.56	1116%	7%	4%	16%
	12	1.19	100.66	4216.33	4089%	12%	4%	24%
2000	13	2.96	17.83	4030.97	22508%	−11%	−14%	−52%
	14	1.92	20.05	1243.43	6102%	−13%	−16%	77%
2500	15	2.38	37.84	2871.57	7488%	90%	7%	645%
	16	2.75	4.3	3769.9	87474%	−35%	−29%	−3%
	17a	1.12	32.72	1778.88	5337%	5%	9%	−85%
3000	18	2.83	31.9	4856.34	15124%	−26%	−9%	32%
	19	0.82	31.09	2505.54	7958%	−15%	−10%	28%
3500	20a	0.38	64.06	822.76	1184%	−19%	−20%	−86%
	21	0.73	179.39	620.32	246%	4%	−5%	−41%
	22	1.32	8.94	4010.93	44785%	2%	−11%	31%
4000	23	1.94	3.79	3875.33	102036%	−8%	−13%	53%
	24	2.61	19.76	3296.24	16581%	−9%	−10%	−35%
4500	25	0.83	2.34	3308.53	141366%	−11%	−15%	−61%
	26ab	1.90	22.54	3096.78	13639%	20%	3%	−87%
	27	0.90	20.13	4362.27	21567%	8%	11%	−16%
5000	28	1.89	11.83	5467.32	46101%	−8%	6%	155%
	29b	1.04	9.77	2010.24	20469%	10%	13%	26%
	30b	1.95	5.65	2132.26	37626%	−80%	−73%	−64%

^a0.41-log antiviral response at week 4.

^b0.41-log antiviral response at week 2.

AST: aspartate transaminase, ALT: alanine transaminase, Fib-4: Fibrosis-4 Score, mg: milligram, no.: number, μg/L: microgram per liter.