Table 1. Distribution of alleles and genotypes of rs7927894 among patients and controls.
| Disease | Genotypes | Allele freq. | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Affected | Controls | Affected | Controls | OR allelic (CI) |
P (Pcorr.) |
|||||||||
| N | CC | CT | TT | N | CC | CT | TT | N | ‘T’ | N | ‘T’ | |||
| n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
n (%) |
|||||||
| AD | 270 | 101 (37) |
128 (47) |
41 (15) |
540 | 254 (47) |
233 (43) |
53 (10) |
540 | 210 (39) |
1080 | 339 (31) |
1.39 (1.12–1.73) |
0.003 (0.033) |
| pAR | 589 | 236 (40) |
265 (45) |
88 (15) |
1178 | 538 (46) |
512 (44) |
128 (11) |
1178 | 441 (37) |
2356 | 768 (33) |
1.24 (1.07–1.43) |
0.0043 (0.047) |
| pAR—AD | 521 | 211 (41) |
237 (46) |
73 (14) |
See above | See above | See above | See above | 1042 | 383 (37) |
See above | See above | 1.20 (1.03–1.40) |
0.018 |
| pAR + AD | 68 | 25 (37) |
28 (41) |
15 (22) |
See bove | See above | See above | See above | 136 | 58 (43) |
See above | See above | 1.54 (1.08–2.18) |
0.015 |
| AA ECAP | 186 | 80 (43) |
80 (43) |
26 (14) |
372 | 170 (46) |
155 (42) |
47 (13) |
372 | 132 (35) |
744 | 249 (34) |
1.09 (0.84–1.42) |
0.50 |
| AA Szcz. | 208 | 78 (38) |
94 (45) |
36 (17) | 200 | 82 (41) |
98 (49) |
20 (10) |
416 | 166 (40) |
400 | 138 (35) |
1.26 (0.95–1.68) |
0.11 |
| AA Wroc. | 92 | 33 (36) |
40 (43) |
19 (21) |
87 | 25 (29) |
49 (56) |
13 (15) |
184 | 78 (42) |
174 | 75 (43) |
0.97 (0.64–1.48) |
0.89 |
| Combined | 486 | 191 (40) |
214 (44) |
81 (17) |
659 | 277 (42) |
302 (46) |
80 (12) |
972 | 376 (39) |
1318 | 462 (35) |
1.17 (0.98–1.39) |
0.075 |
N–total number of allele/subjects in a group; n–number of particular alleles/genotypes; Pcorr.—P values corrected for the number of comparisons (N = 11) by Bonferroni method