Table 3. Distribution of 4 locus (rs7927894, rs7930763, rs2513517, rs7125552) or 2 locus (rs7927894, rs7125552) haplotypes among subjects with AD and controls.
Disease | Haplotype | Affected | Control | OR | P value |
---|---|---|---|---|---|
AD | TATA | 0.26 | 0.24 | 1.12 | 0.36 |
CGTA | 0.04 | 0.04 | 0.97 | 0.9 | |
CGCA | 0.01 | 0.01 | 0.90 | 0.83 | |
TATG | 0.12 | 0.07 | 1.92 | 0.00021* | |
CATG | 0.02 | 0.02 | 0.83 | 0.62 | |
CGTG | 0.08 | 0.09 | 0.89 | 0.56 | |
CACG | 0.10 | 0.13 | 0.76 | 0.01 | |
CGCG | 0.36 | 0.39 | 0.87 | 0.2 | |
AD | TA | 0.26 | 0.24 | 1.12 | 0.37 |
CA | 0.06 | 0.06 | 0.94 | 0.78 | |
TG | 0.13 | 0.07 | 1.98 | 0.000095# | |
CG | 0.55 | 0.63 | 0.73 | 0.0034 | |
pAR | TA | 0.27 | 0.24 | 1.13 | 0.15 |
CA | 0.05 | 0.06 | 0.92 | 0.593 | |
TG | 0.10 | 0.08 | 1.32 | 0.023 | |
CG | 0.58 | 0.62 | 0.84 | 0.019 |
*Pcorrected = 0.002
#Pcorrected = 0.001