Table 1. Significant behavioral findings and trends in Slc1a1^+/- and Slc1a1^-/- vs. WT mice.

Fraction of Alternation in Y-Maze
	DF	Mean Square	F-Value	P-Value	Power	Dunnett's post-hoc test
Sex	1	4.26E-06	0	0.9674	0.0502	Comparison	Count	Mean	Signif?
Genotype	2	0.0167	6.67	0.0048	0.8774	WT	9	0.2674
Sex * Genotype	2	5.06E-05	0.02	0.9800	0.0527	HET	16	0.1890	Yes
Cohort	3	0.0058	2.33	0.0989		MUT	9	0.2098	Yes
Number of Broken Alternations in Y-Maze
	DF	Mean Square	F-Value	P-Value	Power	Dunnett's post-hoc test
Sex	1	0.1103	0.03	0.6102	0.0787	Comparison	Count	Mean	Signif?
Genotype	2	15.7397	3.58	0.0017	0.9401	WT	9	3.5153
Sex * Genotype	2	7.5529	0.06	0.9422	0.0580	HET	16	5.9399	Yes
Cohort	3	17.4752	1.57	0.2204		MUT	9	5.1586	Trend*
Ratio of Time Spent in Center: Edges in OF
	DF	Mean Square	F-Value	P-Value	Power	Dunnett's post-hoc test
Sex	1	0.0009	0.027	0.9674	0.0502	Comparison	Count	Mean	Signif?
Genotype	2	0.0281	8.34	0.0048	0.8774	WT	9	0.1696
Sex * Genotype	2	0.0002	1.72	0.9800	0.0527	HET	16	0.0773	Yes
Cohort	3	0.0053	3.97	0.0989		MUT	9	0.0725	Yes
Fraction of Time Spent in Object Zones: Background in NOR
	DF	Mean Square	F-Value	P-Value	Power	Dunnett's post-hoc test
Sex	1	0.1123	1.06	0.9674	0.1682	Comparison	Count	Mean	Signif?
Genotype	2	0.6176	5.85	0.0048	0.8295	WT	9	1.0412
Sex * Genotype	2	0.0101	0.1	0.9800	0.0630	HET	16	0.5676	Yes
Cohort	3	0.0385	0.36	0.0989		MUT	9	0.6758	Yes
PPI of Startle Reflex
	DF	Mean Square	F-Value	P-Value	Power	Dunnett's post-hoc test
Sex	1	0.0319	0.9	0.3508	0.1499	Comparison	Count	Mean	Signif?
Genotype	2	0.1343	3.81	0.0360	0.6380	WT	9	0.4754
Sex * Genotype	2	0.0020	0.06	0.9462	0.0575	HET	16	0.2546	Yes
Cohort	3	0.0015	0.04	0.9881		MUT	9	0.3052	Trend*

* Trend defined as a change in the same direction as HET that exceeded the 95^th CL of the WT mean