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. 2017 Sep 8;12(9):e0184333. doi: 10.1371/journal.pone.0184333

Table 3. Comparison of different parameters in predicting death due to progressive heart failure or the occurrence of overt heart failure.

Variables Optimal cut-off value Sensitivity Specificity PPV NPV Overall accuracy
Homoarginine 1.08 μmol/l 93.8% 85.3% 46.9% 99.0% 86.4%
NT-proBNP 341.2 pg/ml 87.5% 78.5% 35.9% 97.8% 79.6%
NYHA functional class 2.5 76.5% 96.6% 76.5% 96.6% 94.0%
Ejection fraction of SV 37.1% 50.0% 94.8% 57.1% 93.2% 89.3%
VTI above aortic valve 19.7 cm 57.1% 86.1% 33.3% 94.3% 83.0%
γGT 57.5 U/l 75.0% 71.9% 27.3% 95.3% 72.3%
Albumin 43.5 g/l 66.7% 87.5% 47.6% 93.9% 84.5%

PPV, positive predictive value; NPV, negative predictive value; NYHA, New York Heart Association; SV, systemic ventricle; VTI, velocity time integral