Table 5. JPred4 predicted secondary structure proportions for S/T in the MSS and USS datasets.
| Modified (MSS) | Unmodified (USS) | p value | |||
|---|---|---|---|---|---|
| Secondary structure | Proportion (n) | 95% CI [lower, upper] | Proportion (n) | 95% CI [lower, upper] | |
| C | 0.88 (1,205) | [0.86, 0.90] | 0.829 (83,150) |
[0.826, 0.831] | <0.01 |
| H | 0.08 (106) |
[0.07, 0.09] | 0.126 (12,684) |
[0.124, 0.128] | <0.01 |
| E | 0.05 (66) | [0.04, 0.06] | 0.045 (4,495) | [0.044, 0.046] | 0.6 |
95% CI– 95% confidence interval; n–the number of S/T; the p value refers to the two-tailed z-score test between the modified and unmodified groups.