Table 1. Morphology parameters of MCF-7 cells: Cell a.
Cell parameter | Symbol | Unit | mean ± std b | p-value | |
---|---|---|---|---|---|
viable (n = 101) | apoptotic (n = 105) | ||||
Grid perimeter | GPc | μm | 7047±2642 | 9140±4719 | 1.17E-04 |
Surface area | Sc | μm2 | 1663±448.4 | 1637±561.4 | 7.14E-01 |
Volume | Vc | μm3 | 3681±1560 | 3409±1730 | 2.39E-01 |
Surface-to-volume ratio | SVrc | μm-1 | 0.475±0.0658 | 0.521±0.121 | 8.48E-04 |
Inflection point number | Nsi | - | 7.277±6.854 | 16.57±16.14 | 2.55E-07 |
Surface irregularity index | SIic | μm-1/2 | 116.6±27.94 | 156.7±59.01 | 3.53E-09 |
Equivalent radius | ERc | μm | 9.420±1.217 | 9.102±1.478 | 9.41E-02 |
Volume sphericity index | VSic | - | 0.6828±0.0356 | 0.6592±0.0670 | 1.83E-03 |
Mean mem-to-cen distance b | <Rc> | μm | 9.447±1.252 | 9.257±1.560 | 3.36E-01 |
std of Rc b | ΔRc | μm | 0.5275±0.2723 | 0.7933±0.3876 | 4.35E-08 |
a Parameters in blue fonts present statistically significant differences between the two groups with n as cell number.
b mem-to-cen = membrane-voxels-to-centroid, std = standard deviation.