Table 3. Mean, median, 95% CI for mean and 2.5th-97.5th percentile of clinical chemistry reference values in relation to age profile of healthy adults in Gojjam, Zones, Amahra National Regional State,Northwest Ethiopia.
| Age (years) | ALT (U/L) | AST (U/L) | ALP (U/L) | Amylase (U/L) | LDH (U/L) | Creatinine (μmol/l) | Total Protein (g/l) | Total Bilirubin (μmol/l) | Direct Bilirubin (μmol/l) | |
|---|---|---|---|---|---|---|---|---|---|---|
| 18–24 | Mean | 16.8 | 21.5 | 160.2 | 141.6 | 319.6 | 61.9 | 68.1 | 17.3 | 4.1 |
| Median | 16.0 | 21.0 | 163.0 | 147.0 | 355.0 | 61.9 | 67.2 | 15.4 | 3.4 | |
| 95% CI for mean | 16.0–17.7 | 20.5–22.4 | 152.4–167.9 | 136.0–147.3 | 304.6–334.6 | 59.3–64.5 | 66.5–69.7 | 15.9–18.7 | 3.6–4.6 | |
| 2.5th-97.5th Percentile Range | 6.0–32.7 | 9.3–38.0 | 51.4–234.4 | 57.7–190.0 | 130.0–404.1 | 20.6–101.9 | 53.0–86.8 | 4.2–37.6 | 0.2–13.7 | |
| 25–34 | Mean | 20.2 | 22.2 | 164.3 | 137.6 | 330.6 | 63.8 | 71.9 | 18.1 | 4.8 |
| Median | 19.0 | 22.0 | 165.0 | 143.5 | 353.5 | 64.5 | 74.7 | 15.9 | 4.1 | |
| 95% CI for mean | 18.5–22.0 | 20.8–23.6 | 154.9–173.7 | 129.4–145.7 | 312.8–348.4 | 60.1–67.5 | 69.8–73.9 | 16.4–19.8 | 4.2–5.5 | |
| 2.5th-97.5th Percentile Range | 5.0–45.0 | 7.0–39.0 | 48.8–238.2 | 20.8–187.1 | 158.5–402.5 | 9.7–111.4 | 52.9–86.7 | 3.7–36.1 | 0.2–13.7 | |
| 35–44 | Mean | 19.0 | 21.6 | 158.0 | 138.8 | 317.1 | 59.0 | 68.2 | 18.8 | 4.5 |
| Median | 17.0 | 20.5 | 157.0 | 144.0 | 348.0 | 58.3 | 67.7 | 14.7 | 3.9 | |
| 95% CI for mean | 16.6–21.3 | 19.5–23.7 | 140.5–175.4 | 128.3–149.3 | 295.1–339.0 | 52.2–65.9 | 65.5–70.9 | 15.4–22.2 | 3.5–5.5 | |
| 2.5th-97.5th Percentile Range | 4.4–44.0 | 6.4–39.0 | 45.8–238.3 | 53.6–187.3 | 153.3–405.0 | 10.4–144.0 | 53.6–86.2 | 3.7–38.7 | 0.24–14.8 | |
| 45–54 | Mean | 17.4 | 21.8 | 161.3 | 135.7 | 318.8 | 63.9 | 66.33 | 16.8 | 5.9 |
| Median | 16.0 | 21.0 | 151.0 | 126.0 | 349.5 | 61.9 | 65.7 | 13.5 | 5.7 | |
| 95% CI for mean | 14.2–20.7 | 19.3–24.3 | 144.1–178.6 | 121.7–149.7 | 287.4–350.1 | 56.2–71.5 | 62.7–70.0 | 12.8–20.9 | 4.1–7.6 | |
| 2.5th-97.5th Percentile Range | 3.0–35.0 | 9.0–38.0 | 93.0–232.0 | 57.0–181.0 | 132.0–403.0 | 23.0–114.9 | 53.0–82.2 | 7.7–37.6 | 0.2–16.4 | |
| 55–64 | Mean | 14.2 | 21.4 | 144.7 | 136.1 | 345.2 | 62.7 | 66.6 | 15.1 | 6.5 |
| Median | 14.0 | 21.0 | 142.0 | 141.0 | 364.0 | 59.2 | 63.8 | 14.19 | 5.6 | |
| 95% CI for mean | 11.4–17.1 | 17.3–25.5 | 107.3–182.1 | 109.4–162.8 | 297.7–392.7 | 51.1–74.3 | 60.2–73.0 | 7.9–22.2 | 2.7–10.2 | |
| 2.5th-97.5th Percentile Range | 8.0–22.0 | 11.0–33.0 | 92.0–211.0 | 57.0–186.0 | 215.0–400.0 | 23.0–87.5 | 57.0–81.8 | 3.1–34.4 | 0.2–16.1 | |
| ≥ 65 | Mean | 20.2 | 23.6 | 167.3 | 184.0 | 347.0 | 70.2 | 74.6 | 20.9 | 3.8 |
| Median | 20.0 | 23.0 | 176.0 | 183.0 | 347.0 | 63.6 | 75.4 | 19.7 | 3.6 | |
| 95% CI for mean | 15.3–25.1 | 20.4–26.8 | 41.73–292.9 | 177.4–190.6 | 136.0–358.0 | 33.0–107.0 | 70.0–79.3 | 5.1–47.0 | 2.6–4.9 | |
| 2.5th-97.5th Percentile Range | 15.0–25.0 | 21.0–28.0 | 113.0–213.0 | 71.0–187.0 | 325.0–369.0 | 43.3–114.9 | 72.5–76.0 | 11.1–32.0 | 2.2–6.8 | |
| p-value | 0.003 | 0.952 | 0.96 | 0.54 | 0.798 | 0.695 | 0.107 | 0.974 | 0.092 | |