Table 1. Clinicopathological Characteristics of Breast Cancer Patients (n=416) in the NCI-SEER Connecticut Tumor Registry (2000-07).
| White n =214 | AA/B n=202 | P-Value1 | |
|---|---|---|---|
|
| |||
| TNBC | |||
| ER- PR- HER2- | 35 (16.4) | 52 (25.7) | |
| Non-TNBC | <0.01 | ||
| ER- PR- HER2+ | 6 (2.8) | 20 (9.9) | |
| ER/PR+ HER2- | 143 (66.8) | 117 (57.9) | |
| ER/PR+ HER2+ | 30 (14.0) | 13 (6.4) | |
|
| |||
| Vital Status | |||
| Alive | 166 (77.6) | 133 (65.8) | <0.01 |
| Dead | 48 (22.4) | 69 (34.2) | |
| Median follow-up time (Among Alive)3 | 9.7 yrs | 10.3 yrs | 0.22 |
|
| |||
| Cause of Death | |||
| Breast Cancer | 21 (43.8) | 35 (50.7) | |
| Other Cancer | 8 (16.7) | 8 (11.6) | 0.81 |
| CVD | 6 (12.5) | 7 (10.1) | |
| Other | 13 (27.1) | 19 (27.5) | |
|
| |||
| Histological Sub-Type | |||
| Ductal | 124 (57.9) | 127 (62.9) | |
| Lobular | 24 (11.2) | 12 (5.9) | 0.04 |
| Mixed Ductal/Lobular | 52 (24.3) | 37 (18.3) | |
| Other | 14 (6.5) | 26 (12.9) | |
|
| |||
| Tumor Grade | |||
| I | 25 (12.1) | 22 (11.5) | |
| II | 93 (45.1) | 73 (38.2) | 0.04 |
| III/IV | 88 (42.7) | 96 (50.3) | |
|
| |||
| Tumor Size, Mean (SD) | 2.07 cm (1.5) | 2.26 cm (1.6) | 0.22 |
|
| |||
| Positive Axillary Nodes,4 Mean (SD) | 3.35 (3.9) | 6.67 (16.3) | 0.11 |
|
| |||
| SEER Summary Stage | |||
| Local | 145 (67.8) | 119 (58.9) | |
| Regional | 66 (30.8) | 73 (36.1) | 0.04 |
| Distant | 3 (1.4) | 10 (5.0) | |
|
| |||
| First-Course Chemotherapy5 (Yes) | |||
| Local | 42 (32.3) | 41 (39.4) | 0.27 |
| Regional | 47 (75.8) | 50 (73.5) | 0.84 |
1
Chi-square test for categorical data and independent t-test for continuous variables
2
n (%) except where noted
3
Non-parametric Test of Medians
4
Among patients with Regional Summary Stage (n=63 White; n=66 AA/B)
5
Too few patients with Distant disease (n=12) to perform reliable analyses