Table 4. Linear models for association with cardiac remodeling parameters.
Adjustments as specified in text. Abbreviations: LVMI, LV mass index; LVEDVI, LV end-diastolic volume index; LVMtoV, LV mass-to-volume ratio; LVEF, LV ejection fraction
| Predictor | Outcome | Estimated β Coefficient | Standardized β Coefficient | Adjusted P-Value |
|---|---|---|---|---|
| Pericardial Fat (ml/m) | LVMI (g/m2) | Quadratic: 0.0004 ± 0.00004 | Quadratic: 0.12 ± 0.01 | Quadratic: <0.0001 |
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| LVEDVI (ml/m2) | Linear: 0.005 ± 0.005 | Linear: 0.02 ± 0.02 | Linear: 0.30 | |
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| LVMtoV (g/ml) | Quadratic: 0.00001 ± 0.000001 | Quadratic: 0.12 ± 0.02 | Quadratic: <0.0001 | |
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| LVEF (%) | Linear: 0.04 ± 0.02 Quadratic: −0.0003 ± 0.0001 |
Linear: 0.12 ± 0.05 Quadratic: −12 ± 0.05 |
Linear: 0.01 Quadratic: 0.01 |
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| Liver | LVMI (g/m2) | Linear: −0.07± 0.01 | Linear: −0.10 ± 0.01 | Linear: <0.0001 |
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| Attenuation (HU) | ||||
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| LVEDVI (ml/m2) | Linear: 0.12 ± 0.04 Quadratic: −0.001 ± 0.0004 |
Linear: 0.20 ± 0.07 Quadratic: −0.26 ± 0.07 |
Linear: 0.004 Quadratic: 0.0002 |
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| LVMtoV (g/ml) | Linear: −0.005 ± 0.002 Quadratic: 0.00004 ± 0.0000 |
Linear: −0.24 ± 0.07 Quadratic: 0.18 ± 0.07 |
Linear: 0.0007 Quadratic: 0.01 |
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| LVEF (%) | Linear: 0.01 ± 0.01 | Linear: 0.02 ± 0.02 | Linear: 0.27 | |
Adjusted for age, sex, race/ethnicity, excess BMI, excess waist circumference, cigarette smoking status, total intentional exercise, HOMA-IR, C-reactive protein, diabetes status, systolic blood pressure, hypertension medication use, LDL and statin medication use. Models where pericardial fat was the primary predictor of interest were also adjusted for hepatic fat and vice versa.