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. 2017 Sep 8;7:10974. doi: 10.1038/s41598-017-11387-7

Table 1.

Comparison of the performance on Ebola antigen detection between the current FET biosensor and other published works/commercial products. For limit of detection, some studies utilized pfu/ml as a measure of virus concentration, while other studies including ours utilized ng/ml for protein concentration. There is no direct conversion between the two units.

Technique Target Dispersion medium Limit of detection Processing time
Our work FET EGP PBS, serum, plasma 1 ng/ml within a few seconds
ReEBOVTM chromatography VP40 blood, plasma 625 ng/ml 15–25 min
Duan et al.9 chromatography EGP serum 100 ng/ml 30 min
Yen et al.8 chromatography EGP serum 150 ng/ml
Daaboul et al.10 single-particle interferometric reflectance imaging sensor pseudotyped Ebola virus blood, serum 5 × 103 pfu/ml 2 h
Yanik et al.12 opto-fluidic nanoplasmonic pseudotyped Ebola virus PBS 106 pfu/ml 90 min
Cai et al.11 opto-fluidic chip Ebola RNA water 0.2 pfu/ml 3–10 min