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. 2017 Sep 8;7:11038. doi: 10.1038/s41598-017-10633-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Minimum HD allele frequency in the first 100 generations after SR release for various fitness costs, initial conditions, and release ratios. See Fig. 3 for details. Similarly to the RD, the SR is least likely to eliminate a target HD when its fitness costs are large, and when the release yields post-release frequencies near the equilibrium, though equilibrium frequencies are not identical to RDs. In some of the simulations, the system is not yet at equilibrium, and the HD is still decreasing in frequency at 100 generations.